In the suburban 48th research Institute of the Ministry of defence on 3 June net profit of 50 volunteers-military personnel for clinical trials of new vaccines against coronavirus. The first phase of the experiment is to determine whether the drug is safe for the human body. In connection with the possible risks have been selected the most physically strong and healthy people. According to experts, after a vaccination volunteers may experience discomfort, because the drug is created based on the DNA of adenovirus causing fever and fever. But under the supervision of military doctors everything should go normally.
In the laboratory of the Institute of the Ministry of defence, is usually closed to outsiders, is hard work on creating the first Russian vaccine against the coronavirus. She is in the final phase of human trials.
Volunteers were many, but for clinical trials selected only 50. That warrant officers and officers aged 25 to 50 years, 45 men and 5 women, including 10 health workers.
“the Selection of candidates was performed among contract servicemen, as the test on appeal is prohibited by the legislation of the Russian Federation. Very important before starting research is to prevent the infection of volunteers, so they and the medical staff will be in isolation,” — said the head of the main military clinical hospital named after academician N. N. Burdenko Eugene Hooks.
the Crew of our channel, when she was tested on animals, visited the heart Institute and saw the mobile labs operating in Italy and Serbia. This experience in infectious foci is of course used when creating the vaccine. Preclinical testing, during which all animals revealed an immune response to the serum took two months. Development Institute of the Ministry of defence has engaged in cooperation with the National researchm centre of epidemiology and Microbiology named Gamalei. On completing the tests Sergei Shoigu reported to Vladimir Putin on may 26.
a recombinant Vaccine that is created using genetic engineering. As a rule, the scheme of the creation of these vaccines is this: does the so-called vector — virus-pacifier — it serves as a vehicle. It is placed in the coronavirus. This hybrid goes into human cells, triggering the body’s immune response. These vaccines scientists around the world are considered the most secure.
“Previously, specialists of the 48th Institute has been proven the efficacy and safety of this drug on large laboratory animals, and small monkeys and hamsters”, — said the head of the 48th Central research Institute of the Ministry of defense Sergei Borisevich.
in rodents during the course of the disease was observed a familiar clinical picture: light on the x-rays look like frosted glass. For the last stage of pre-clinical trials have chosen Javanese macaques, whose pulmonary system is most similar to human.
Military Institute of Microbiology for 92 years of its history developed dozens of vaccines and sera. Among the latest vaccine against Ebola, middle East respiratory syndrome, known as MERS — he is also from the family of coronaviruses, only much more dangerous.
Russia is getting closer to getting a vaccine. We start clinical tests on volunteers were among the first in the world. In this final stage is required to confirm the safety and immunogenicity, in other words — the effectiveness of the drug. If the tests are successful, the vaccine is sent to the pipeline.
