Some patients with mild COVID-19 may not recover for months

Graphic designers have created the most detailed and accurate from a scientific point of view a 3D model of coronavirus. Visualization allows to better understand how this actually fairly complex molecular machine less than a thousandth the thickness of a human hair.

What we’re able to consider? First of all, club-shaped proteins with which SARS-CoV-2 clings to the cell membrane. He then injects its own genome RNA. Chains of amino acids neatly packaged inside the capsid. The main task of a virus to multiply, therefore, infected cells immediately transformed into factories for the Assembly of new pathogenic particles. The invader will use their resources until they perish.

fortunately, our body has to respond. The immune system starts to produce antibodies, these special molecules are stuck to each virion, and ultimately destroy it.

However, this is not always happening quickly. Doctors from Europe and the United States is concerned about the high number of cases of abnormally long current COVID-19.

According to, again, the British statistics, the average recovery from a coronavirus is 7-12 days. But about every 20th patient is ill for 25 days and more (we are talking about people with mild infections usually they are treated at home). The disease is not necessarily accompanied by heat, there may be no cough. But there are often severe headache and sore throat. Symptoms that are increasing, almost disappear. Experts say it is also quite painful.

“It’s actually very hard. Maybe better to settle for 2 days with a temperature of 40 than 60 days with a temperature of 37.1. This, too, is. This is one of about 20 people. And it may not be after a severe course. Until we understand at the level of pathophysiology that distinguishes people with a moderate and protracted period of moderate flow. We are working on it and definitely this will understand”, — assured Ancha Baranova, Professor, school of systems biology Of George Mason University.

what is the maximum can continue such a state? The record still holds a resident of Utah. Her body unsuccessfully struggling with COVID for 70 days, no medications help. On March 31 it passed test positive for coronavirus. A couple of weeks thought she just SARS.

“it’s a test it’s been 1.5 months. Of course, I was sure that the new test, which I passed recently, will be negative. But again he was positive! Some days better, some worse. But I still don’t feel normal. I get headaches, muscle aches. Although, in General, I think that my case can be called easy,” — said the woman.

the Most unpleasant thing that all this suffering may not even be rewarded. The body of such people will not get protection from the coronavirus in the future. Because patients undergoing COVID-19 in the form of light, usually don’t have enough to develop immunity number of antibodies.

“There is a dependence between the strength of the disease, and specifically one of the parameters is the level of C-reactive protein, which indicates the level of inflammation and the probability of the development we have a strong immune system. That is, the more we have, the virus causes inflammation in the body, the more we have of neutralizing antibodies,” explained Ancha Baranova.

of Course, sometimes immunity to coronavirus produced even in asymptomatic carriers. Moreover, so powerful that in the future they can become plasma donors. But it is rather an exception from the rule.

Text: Meteotest