Clinical trials of the vaccine against coronavirus COVID-19 will start in the coming days. The first group of volunteers to be vaccinated, is now in isolation. Preclinical testing of drugs for safety and antibody production have yielded positive results. How many vaccines can give the mass pharmaceutical market? At what stage is the development of efficient means of virus? And what research centers have advanced further than others?
the Military oath does not imply participation in clinical trials, but it is also a matter of honor — contribution to the health of the nation.
– Hello, how are you?
Alexander, adjutant of the Military medical Academy. Now writing a thesis, and personal experience of testing the vaccine may become the basis for the practical part of scientific work.
“I Myself, as a cadet, he began to donate blood plasma. Are honorary donor, so I’m used to it, — says the volunteer Alexander. — So not particularly worried and didn’t hesitate when offered”.
officers, warrant Officers, contract servicemen only voluntarily participate in the test — they tested for coronavirus and antibodies thereto. Along with them in the clinical phase of studies will take part civil. Artem is not the first time called to volunteer.
“It is now, I deliberately went, because I know that nothing will happen. And when did the vaccine for Ebola, for me it was the unknown,” — says the volunteer test vaccines Artem.
the Vaccine, jointly developed by the Institute of Microbiology Minooborony and Research center named after N. F. Gamalei, successfully tested on animals. Clinical studies of the Ministry of defence plans to complete by the end of July 2020.
“the Psychological state of our volunteers is good. Set up cheerfully and confidently” — said the head of Department of the main military clinical hospital named after academician N. N. Burdenko Viktor Pavlov.
Anticipatedll that in the near future in Russia will be registered three vaccines. In addition to the development of the Institute name Gamalei, are drugs of the Novosibirsk Center “Vector” and the St. Petersburg Institute of vaccines and serums Federal medical-biological Agency.
Russia is now developing several types of vaccines with different mechanism of action. And they are all at different stages — in some institutions are beginning to test on volunteers, others are still in preclinical tests. But the important work of each research Institute, the vaccine requires a large part of the population of Russia, and vaccines need a lot.
At the Institute of experimental medicine drinking create a vaccine based probiotic. It tastes like fermented baked milk. Now carry out tests on mice.
“We don’t know the results, but ideally, the antigen together with lactic acid products, appear to be antigen-presenting cells to produce antibodies specific against this protein,” explains head of the Department of molecular Microbiology Institute of experimental medicine, doctor of medical Sciences Alexander Suvorov.
the Institute of influenza, name Smorodintseva develop a vaccine based on the flu virus.
“was taken from a weakened flu virus, his part, and fixed the virus code, which must start the immune response,” says about the technology of vaccine development, acting Director of the influenza research Institute named after A. A. Smorodintseva Dmitry Lioznov.
of the 120 candidate vaccines against coronavirus, registered in the world health organization, Russian 8. This is a great contribution, said the who representative in Russia.
“a lot of developments, — stressed the who representative in Russia, Melita Vujnović. — And who expects that Russia will share experience.”
And in anticipation of a vaccine against coronavirus, scientists are advised to get vaccinated against influenza, if concerns about the second wave of fall come true, it can save you from many complications. The combination of flu and COVID-19 more dangerous than the coronavirus itself.
“this virus just have to learn to live. Why don’t you consider such complications? Because we have learned to treat it, know which patients require hospitalization, which are not. I think the losses will be much less in this the second wave, as all it is called”. – said academician of RAS, head of chair of Microbiology, Virology and immunology sechenovskiy University Vitaly Zverev.
For the scientists is a big challenge: the faster a vaccine will be, the more lives will be saved. While the optimistic forecasts of industrial production of the vaccine could begin in Russia in September 2020.